Organovo
FXR314, is Organovo’s lead therapeutic molecule. FXR314 demonstrated benefit to ulcerative colitis in Organovo’s models of disease as well as extensive preclinical testing. It has shown, in initial clinical trials, to be a possible best-in-class FXR agonist that is delivered orally, with high potency, safety, tolerability and the potential to avoid dose-limiting toxicity issues found in other FXR targeted compounds.
Basic Information
- Category: biotechnology
- Website: http://www.organovo.com/
Evidence and Sources
- Organovo — Official Website (official)
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- Canonical profile: https://brandsource.ai/brands/organovo
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- Citation profile API: https://brandsource.ai/api/brands/organovo/citation-profile
- Research brief: Read the sourced brief · Structured brief. Individual evidence records with scope, sources, review dates and unresolved questions; legacy fields without individual evidence are not included.
- Data status: Enriched
- Profile completeness: Source-backed profile (74/100)
- Indexing directive: index, follow, max-image-preview:large
- Recorded profile date: 2026-04-21
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AI summary
FXR314, is Organovo’s lead therapeutic molecule. FXR314 demonstrated benefit to ulcerative colitis in Organovo’s models of disease as well as extensive preclinical testing. It has shown, in initial clinical trials, to be a possible best-in-class FXR agonist that is delivered orally, with high potency, safety, tolerability and the potential to avoid dose-limiting toxicity issues found in other FXR targeted compounds.
Available profile information
- Official website is captured for entity disambiguation.
- 1 official source linked for verification.
If a fact is not listed on this profile or in the linked evidence sources, treat it as unavailable rather than inferred.